CrystalsFirst

Mastering Diverse Protein Crystal Morphologies: Plates, Needles, Blocks & Prisms

…over the years, we have handled protein crystals in many different morphologies and behaviour.

Working successfully across such a diversity takes broad expertise, automation and reliable technology.

By successfully applying SmartSoak® technology in high-throughput co-structure determination workflows, we generate the structural data that helps medicinal chemistry and structure-based drug design move faster.

Our experience spans across:
– diverse target classes: E3 ligases, transcription factors, GTPases, helicases, phosphatases, and kinases,
– different binding mechanisms: non-covalent and covalent,
– different type of ligands: small molecules, macrocycles, molecular glues, and PROTACs.

Crystal diversity is part of the job – turning it into actionable structural insight is where expertise matters.

 

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