Mastering Diverse Protein Crystal Morphologies: Plates, Needles, Blocks & Prisms
…over the years, we have handled protein crystals in many different morphologies and behaviour.
Working successfully across such a diversity takes broad expertise, automation and reliable technology.
By successfully applying SmartSoak® technology in high-throughput co-structure determination workflows, we generate the structural data that helps medicinal chemistry and structure-based drug design move faster.
Our experience spans across: – diverse target classes: E3 ligases, transcription factors, GTPases, helicases, phosphatases, and kinases, – different binding mechanisms: non-covalent and covalent, – different type of ligands: small molecules, macrocycles, molecular glues, and PROTACs.
Crystal diversity is part of the job – turning it into actionable structural insight is where expertise matters.