November 17, 2023
September 6, 2023
This year, we celebrate a significant achievement as CrystalsFirst reaches its 5th Anniversary!
For the past five years, CrystalsFirst has been leading the way in pushing the boundaries of structural biology and drug discovery. Our relentless dedication to innovation and outstanding performance has positioned us as a pivotal figure in the field of drug discovery, establishing groundbreaking benchmarks for drug discovery.
We are proud to report our remarkable achievements over the past five years:
THE SMARTSOAK® ADVANTAGE
FOR COVALENT DRUG DISCOVERY
SmartSoak provides significant advantages for for covalent fragment-based drug discovery enabling rapid determination of co-structures for optimization:
Conventional soaking fails to modify the cysteine in the active site
SmartSoak setup enables the covalent modification of cysteine
High resolution co-structure of human protein with novel MOA at 1.3 Å
July 24, 2023
CrystalsFirst and NexMR Join Forces to Supercharge
Fragment-Based Drug Discovery
“This collaboration allows us to provide our clients with a more holistic approach, combining NexMR’s ultrafast NMR fragment screening technology with our world-class protein crystallography expertise. Together, we aim to accelerate the discovery of novel therapeutics.” Dr. Serghei Glinca, CEO of CrystalsFirst GmbH.
May 22, 2023
Co-crystal soaking using our technology SMARTSOAK® is specifically designed for drug discovery purposes:
Contact us today to learn more about our soaking applications!
THE CHALLENGE OF THE INDUSTRY: ACCESS TO CHEMICAL MATTER
The challenge of the industry remains – access to chemical matter. The Drug Discovery Chemistry conference was full of highlights focusing mainly on enabling technologies and platforms that unlock chemical matter. Read our perspective.
March 31, 2023
CrystalsFirst’s innovative platform to unlock chemical matter using FBDD has been featured in the renown “Photon Science 2022 – Highlights and Annual Report” published by Europe’s largest synchrotron DESY.
We believe that putting science first and empower each individual is essential for a great atmosphere and productivity. But we wanted to measure our results.
A GREAT PLACE TO WORK
The results of the “Employee Satisfaction Survey” lead to an index of 80, which reflects a the highest possible level of satisfaction: “very high satisfaction”.
Happy employees, happy customers
March 11, 2023
February 23, 2023
CrystalsFirst Establishes Partnership With Akttyva Therapeutics To SupporAI-Powered Drug Discovery Programs
We are excited to announce today the signing of a drug discovery service agreement with Akttyva Therapeutics to unlock the full therapeutic potential of the human kinome.
January 31, 2023
EXPANDET PROTEIN PRODUCTION CAPABILITIES
Introducing our new state-of-the-art protein production capabilities, specifically designed for drug discovery purposes:
Contact us today to learn more about our new protein production facility and how we can help you achieve your research goals!
THE IMPACT OF THE PROTEIN DATA BANK
Our recent blog post, we discuss how the deposited structural data is helping to develop new drugs, supporting biomedical research, and providing relevant data for Artificial Intelligence and Machine Learning methods.
January 23, 2023
July 7, 2020
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More InformationJune 12, 2025
June 4, 2025
Meet Anne Stone and Serghei Glinca at the BIO International Convention to explore how SmartSoak and FragAI are transforming target enablement and driving milestone success in drug discovery.
April 10, 2025
We invite you to connect with Anne Stone and Serghei Glinca at DDC 2025 to learn how SMARTSOAK® has enabled over 40 challenging drug targets and helped companies achieve their milestones. Our new technology FragAI is leveraging structural data for multi-target drug discovery campaigns.
The 20th Annual Drug Discovery Chemistry conference is taking place in sunny San Diego from April 14-17.
October 1, 2024
Our CEO, Serghei Glinca, is attending Discovery on Target 2024 in Boston! Be sure to connect with Serghei to discover how CrystalsFirst can help to unlock chemical matter using the MAGNET platform.
September 20, 2024
Meet our CEO Serghei Glinca at the Fragment–Based Lead Discovery Conference taking place in Boston from 22nd to 25th of September.
The conference is an opportunity to connect and discuss:
– How SmartSoak® screening enables drug discovery for challenging targets
– Advantages of the “structure first” approach
– Proven technology in over 40 campaigns
September 15, 2024
Our Head of AI Artem German will be participating in the 7th RSC-CICAG / RSC-BMCS Artificial Intelligence in Chemistry Symposium!
This is a great opportunity to learn about cutting-edge AI applications in chemistry. If you’re attending the event, don’t miss the chance to connect with Artem to learn about our novel generative AI application designed for FBDD, scaffold hopping and de novo design.
We’re always eager to discuss how our AI solutions can accelerate your research and development efforts.
September 8, 2024
We invite you to be part of the Pitch Night the CIC (Cambridge Innovation Center). Serghei Glinca will present how our MAGNET platform overcomes challenges in small molecule drug discovery using structural biology and gen AI.
When: Tuesday, September 10th, 5:00 – 7:30 pm
Where: Cambridge Innovation Center – Mosaic Event Space, 1 Broadway, Cambridge, MA 02142
We look forward to seeing you there!
February 27, 2024
Meet our CEO Serghei Glinca at the 7th Sachs Associates’ Annual European Life Sciences CEO Forum taking place in Zurich from 28th to 29th of February.
The event is an opportunity to connect and discuss:
November 25, 2023
Our Head of Protein Sciences Moritz Ruf will be attending the conference on “Engineering recombinant proteins for structural and functional studies”.
November 21, 2023
Our head of AI Artem German will give a talk at the FoldForum on the role of generative AI for drug discovery. CrystalsFirst’s MAGNET platform utilizes generative AI to unlock chemical matter using “crystal structure first” approach.
November 16, 2023
CrystalsFirst will be available for partnering at the EFMC International Symposium on Chemical Biology taking place in Basel from 16th to 18th of November.
The event is an opportunity for networking: let’s connect and discuss
August 11, 2023
CrystalsFirst will be attending ACS Fall 2023 in San Francisco
August 13-17. We will present our solution to unlock chemical matter using “crystal structure first” fragment hits.
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