September 6, 2023
This year, we celebrate a significant achievement as CrystalsFirst reaches its 5th Anniversary!
For the past five years, CrystalsFirst has been leading the way in pushing the boundaries of structural biology and drug discovery. Our relentless dedication to innovation and outstanding performance has positioned us as a pivotal figure in the field of drug discovery, establishing groundbreaking benchmarks for drug discovery.
We are proud to report our remarkable achievements over the past five years:
- integrated target-to-hit platform “putting structural data first”
- unlocking chemical matter for difficult targets
- solutions for covalent and non-covalent drug discovery
- machine learning platform
- more to come…
THE SMARTSOAK® ADVANTAGE
FOR COVALENT DRUG DISCOVERY
SmartSoak provides significant advantages for for covalent fragment-based drug discovery enabling rapid determination of co-structures for optimization:
Conventional soaking fails to modify the cysteine in the active site
SmartSoak setup enables the covalent modification of cysteine
High resolution co-structure of human protein with novel MOA at 1.3 Å